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Study AcronymFull TitleLead OrgLocalitiesStatusMore Info
AcuBack Observational Study Acupuncture for Back Pain: A Mixed Methods Observational Study Evaluating Patient Outcomes and Their Determinants  Pending View details
Addiction Endophenotypes A Study into the Causes and Effects of Stimulant Dependence University of CambridgeNorfolkSet-up View details
AESOPS The effectiveness and cost-effectiveness of opportunistic screening and stepped care interventions for older hazardous alcohol users in primary care.University of YorkNorfolkRecruiting View details
Age differences in cervical screening non-attendance Exploring age differences in reasons for non-attendance for cervical cancer screening in England. University College London Closed View details
An evaluation of rheumatology practioner clinics in primary and secondary care An evaluation of rheumatology practioner clinics in primary and secondary care  NorfolkSet-up View details
ARRISA A cluster randomised controlled trial to assess the effectiveness and costs of implementing asthma risk registers to identify and improve management of high risk asthma patients in primary care.University of East Anglia Follow-up View details
Back On Track: Groups for Women Evaluation of a group based intervention for women with depressionBristol University   View details
BBC-NCRN cohort National Population based study of treatment effect and genetic risk factors for contralateral primary breast cancer in women in Britain (The British Breast Cancer study) BBC NCRN cohort study - check spreadsheetCancer Research UK/London School of Hygiene and Tropical MedicineNorfolk
Cambs
Herts
Essex
Suffolk
Recruiting View details
BeBack A multi-centred randomised controlled trial of a primary care based cognitive behavioural programme for low back pain (LBP). (The BEST Study)Warwick University Closed View details
BEST- BARRETTS Barrett's Oesophagus Screening Trial (BEST)MRC Cancer Cell UnitCambsRecruiting View details
BP-CKD Comparing interventions to lower BP in CKD (QI in CKD)St George's University of LondonCambsFollow-up View details
BRCA Trial Breakthrough Breast Cancer & Cancer Research UK Genetic Breast Cancer Trial: A randomised phase II pilot trial of carbopatin compared to docetaxel for patients with metastatic genetic breast cancer.Cancer Research UK & UCL Cancer Trials Centre Recruiting View details
Building Blocks Evaluating the Family Nurse Partnership Programme in England: a randomised controlled trial Cardiff University Set-up View details
CC75C study Quality of life at the later end of life - a qualitiative and quantitative study of the Cambridge City over-75s CohortUniversity of Cambridge Closed View details
Cequel Comparative Evaluation of QUEtiapine-Lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in people with bipolar depression   Pending View details
CHUMS Care Homes Use of Medicines Study (CHUMS)  Closed View details
CVRA Evaluation Impact on clinical practice of the Joint British Societies? Cardiovascular Risk Assessment Tool.University of Hertfordshire Closed View details
CYMPLA - Can Your Mobile Phone heLp your Asthma? A mobile phone based structured intervention to achieve asthma control in patients with uncontrolled persistent asthma: pragmatic randomised controlled trial University of AberdeenNorfolk
Herts
Suffolk
Follow-up View details
DARE Drug-induced Arrhythmia Risk Evaluation St George's Hospital medical schoolNorfolk
Cambs
Herts
Essex
Suffolk
Beds
Recruiting View details
DeNDRoN 007 Observational study on costs and caregiver burden in Alzheimer?s diseaseInstitute for Aging & Health Wolfson Research Centre Newcastle General Hospital Closed View details
DESCARTE Decision rule for severe symptoms and complications of acute red throat in everyday practice University of SouthamptonHerts
Essex
Recruiting View details
DIALOGUE The DIALOGUE Study: How can patients' experiences contribute to improving care for type 2 diabetes? (Diabetes Learning Opportunities Generated by Users' Experiences)University of Cambridge Closed View details
DNA Lacunar Resource A DNA Resource for Lacunar StrokeSt George's University of LondonCambs
Norfolk
Recruiting View details
DOMINO AD Developing integrated care in primary care for people with serious mental illness   Recruiting View details
DRN 021 ACTION LADA (LRN NELon) Identify and characterise diabetes towards limiting its progression. Institute of Cell and Molecular Science, QMULHertsSet-up View details
DRN 023 ASCEND A randomised 2x2 factorial study of aspirin versus placebo, and of omega-3 fatty acid supplementation versus placebo, for primary prevention of cardiovascular events in people with diabetes.Oxford UniversityCambs
Essex
Herts
Norfolk
Recruiting View details
DRN 044 SAMS The Supported Adherence to Medication Study (SAMS)Universities of Oxford and Cambridge Closed View details
DRN 055 FENLAND (LRN East) The Fenland Study - A population based cohort study of the interaction between environment and genetic factors in determining obesity, insulin sensitivity and hyperglycaemiaCambridge UniversityCambs
Norfolk
Recruiting View details
DRN 059 NDCCS (LRN Eastern) Norfolk Diabetes case control study: a case control study investigating the role of genetic factors in the aetiology of type 2 diabetesCambridge UniversityNorfolk
Cambs
Recruiting View details
DRN 060 ADDITION The Addition study: A randomised controlled trial of the cost-effectiveness of a programme of screening and intensive multifactorial intervention for type 2 diabetes in primary care.University of Cambridge Follow-up View details
DRN 061 ADDITION PLUS (LRN Eastern) Does adding facilitated behaviour change improve outcomes for people with diabetes detected by screening? The Addition Plus studyUniversity of Cambridge Follow-up View details
DRN 195 (ADDITION: 5 year follow up) Anglo-Danish-Dutch study of Intensive Treatment of people with newly diagnosed diabetes in Primary Care (ADDITION) - 5 year follow upCambridge University Set-up View details
DRN 197 (ADDITION-10% study) Evaluation of the benefits and costs (psychological and economic) of screening for type 2 diabetes at the population level. A sub-study of ADDITION. University of CambridgeCambsSet-up View details
DRN 261 RAPSID Can peer support, delivered as a group or individual intervention, enable people with diabetes and improve their health? (A RAndomised controlled trial of Peer Support In Type 2 Diabetes) Cambridge University Set-up View details
DRN080 Reducing cardiovascular risk with Flavonoids in post-menopausal women with Type 2 Diabetes - DRN080UEANorfolkRecruiting View details
DRN082 (DARE) Exeter Research Alliance for Diabetes Study Peninsula Medical SchoolEssex  View details
DRN118 (The DESMOND Lay Educator study) Can Lay Educators deliver structured education programmes as part of a lay educator/health care professional team with the same degree of integrity, quality and efficacy as trained health care professional educators?  Set-up View details
DRN120 (ICPD) Improving the delivery of care for patients with diabetes through understanding optimised team work and organisation in primary care   Pending View details
DRN133 (DESMOND 3 year follow-up) DESMOND Diabetes education and self management for ongoing and newly diagnosed:a randomised control trial of a structured group education programme for people newly diagnosed with Type 2 diabetesLeicester University Hospitals Pending View details
DRN135 (Diabetes Prevention Programme) Delivering the Diabetes Prevention Programme in a UK community setting.University of East AngliaNorfolkSet-up View details
ECLIPSE Effectiveness and cost-effectiveness of Levonorgestrel containing Intrauterine system in primary care against standard treatment for menorrhagiaUniversity of BirminghamCambs
Beds
Recruiting View details
EDIE-2 Early detection and psychological intervention for individuals at high risk of developing psychosisUniversity of ManchesterNorfolk
Cambs
Recruiting View details
EDS erectile dysfunction studyUni HertsHertsRecruiting View details
ENCAM Evaluation of the nursing contribution to models of care of people with long term conditionsCRIPACC / Uni Herts Follow-up View details
EOL- CARE HOMES EOL- CARE HOMES. The experiences and expectations of older people resident in care homes, their carers and professionals of end of life care and symptom relief needs: a prospective study. University of Hertfordshire Cambs
Herts
Essex
Recruiting View details
EPIC - Norfolk Third Health Check Diet, lifestyle and biological determinants of health and chronic disease: The Third Health Check of EPIC-Norfolk. A Prospective Population Study. Cambridge University NorfolkRecruiting View details
ESCAPE Effectiveness of computer-tailored Smoking Cessation Advice in Primary Care: a Randomised Trial UCL Recruiting View details
EUDRAGENE UK component of EUDRAGENE: studying the pharmacogenetics of selected adverse drug reactions (ADRs): identifying possible cases of ADRs through primary care databases and hospitals across the UK London School of Hygiene and Tropical MedicineBeds
Cambs
Essex
Herts
Norfolk
Suffolk
Recruiting View details
Evaluation: THF Co-Creating Health Initiative, v1 The Evaluation of the Health Foundation's Co-Creating Health Initiative (CCHi)Coventry University CambsRecruiting View details
EVIDEM-ED Developoment of an educational intervention for primary care management of psychosocial interventions and shared care of medication for people with dementia. UCL/Central and Northwest London NHS Foundation Trust Set-up View details
FACS A randomised controlled trial to assess the cost-effectiveness of intensive versus no scheduled follow-up in patients who have undergone resection for colorectal cancer with curative intentSouthampton UniversityCambs
Norfolk
Recruiting View details
FEP The Role of Primary Care for Young People with First Episode Psychosis National Primary Care Research and Development Centre Set-up View details
FISH Assessing the impact of escalating fish oil consumption on n-3 PUFA content of transport, storage and functional poolsMRC Human Nutrition Research Follow-up View details
FLU WATCH Flu watch:Community Study of the behavioural and biological determinants of transmission, to inform seasonal and pandemic planning. Cambs
Herts
Recruiting View details
Fluwatch cohort A Community Studies of the Emergence on new Influenza A (H1N1)MRC, GPRF in assoc with UCL, HPA , Oxford UniversityBeds
Norfolk
Cambs
Closed View details
Fluwatch cohort C Community study of the behavioural and biological determinants of influenza transmission to inform seasonal and pandemic planningMRC, GPRF in assoc with UCL, HPA , Oxford UniversityBeds
Cambs
Essex
Herts
Norfolk
Suffolk
Recruiting View details
GNOME A double-blind randomised placebo-controlled trial of topical nasal steroids in 4-11 year old children with persistant bilateral Otitis Media with Effusion (OME) in Primary CareUniversity of Southampton Closed View details
GORD Non-pharmacological group treatment fro GORD (Gastro-oesophaegal reflux disease): an exploratory trial of a specialist nurse-led intervention in primary careKCL/Brent PCT Follow-up View details
HEALTH REFORMS An investigation into the impact of Health Reforms across England     View details
Heatwaves Heatwaves in the UK: impacts and public health responses. Health & social care responses to the Department of Health heatwave Plan for England. UCL Follow-up View details
HPS2-THRIVE HPS2-THRIVE: Treatment of HDL to Reduce the Incidence of Vascular Events: A randomised trial of the long term clinical effects of raising HDL cholesterol with extended release niacin/laropiprnat  NorfolkRecruiting View details
ICICLE-PD Incidence of Cognitive Impairment in Cohorts with Longitudinal Evaluation ? Parkinson?s Disease Newcastle University Set-up View details
IID2 Second Infectious Intestinal Diseases StudyMRC General Practice FrameworkCambs
Essex
Beds
Herts
Recruiting View details
IMAGE Improving Management in GastroenterologyKing?s College London Recruiting View details
IQUIT in practice The ?i-QUIT in practice? trial: A randomised controlled trial of web-based facilitation of smoking cessation advice by practice nursesCambridge UniversityCambs
Essex
Suffolk
Set-up View details
KCS Keeping Children Safe at Home University of East AngliaNorfolkRecruiting View details
Knee self-care study Knee self-care study: Investigation patients health priorities and use of health services. A qualitative exploration   Set-up View details
LanScape LANtuS Combined with APidra Evaluation Sanofi-Aventis  Set-up View details
LD-ROME Relative efficacy and cost-effectiveness of different treatment approaches currently used in the management of epilepsy in people with a learning disability Cambridge UniversityCambs
Norfolk
Recruiting View details
LEGS Trial: Liaison with PCPs and HEIs to Refine Referrals of ARMS LEGS Cluster Randomized Trial: Liaison with Education and General Practices to Detect and Refine Referrals of People with At-Risk_Mental-States (ARMS) Cameo Early Intervention ServicesCambsRecruiting View details
LEVEMIR DRN051 A seven month open labelled randomised multi-centre two-group parallel trial comparing administration of insulin Detemir once daily in the morning versus NPH insulin once daily in the morning in aging subjects with type 2 diabetes. Phase 4  Closed View details
LIFELAX LIFELAX:- Diet and Lifestyle versus laxatives in the management of chronic constipation in older peopleEoEHertsClosed View details
LoTS Care: Stroke System of Care Trial Cluster randomised trial evaluation of a patient and carer-centred system for longer-term stroke care   Set-up View details
Lung-SEARCH A randomised controlled trial of surveillance for the early detection of lung cancer in a high-risk groupUCL trial centreCambsRecruiting View details
MAIN-AD Memantine for the Long Term Management of Neuropsychiatric Symptoms in Alzheimer?s disease King's College LondonNorth Essex Partnership NHS Foundation Trust Set-up View details
MASCOT Management of asthma in School-age children On TherapyKeel University and University Hospital of North StaffordshireNorfolkRecruiting View details
MATREX A single blind randomised controlled trial to determine the effectiveness and cost utility of manual chest physiotherapy techniques in the management of infective exacerbations of Chronic Obstructive Pulmonary Disease. (MATREX)University of East Anglia Follow-up View details
MCRN Vaccine Study A new combination vaccine against 6 childhood diseases   Pending View details
MOLEMATE THE MOLEMATE UK TRIAL: The management of suspicious pigmented lesions in primary careUniversity of CambridgeCambs
Suffolk
Recruiting View details
MORAL ID Moral reasoning amongst offenders with intellectual disabilitiesUEANorfolkRecruiting View details
MRC CFAS II MRC Cognitive Function and Ageing Study (CFAS) CFAS II Cambridge University CambsRecruiting View details
National Evaluation of the Partnerships for Older People Projects (POPP) National Evaluation of the Partnerships for Older People Projects (POPP)University of Hertfordshire Recruiting View details
NCRN067 - SPRAY STUDY A double blind, randomized, placebo controlled, parallel group dose range exploration study of Sativex® in relieving pain in patients with advanced cancer, who experience inadequate analgesia during optimized chronic opioid therapy.G W PharmaNorfolkRecruiting View details
NOAR Norfolk Arthritis Register (NOAR) - flagging of patients for cancer and mortality.Manchester UniversityNorfolkRecruiting View details
NSCCG National Study of Colorectal Cancer GeneticsNNUHNorfolkRecruiting View details
NSECG National Study of the Genetics of Endometrial Cancer: a national collection of unselected cases of endometrial cancer to enable studies to identify inherited factors involved in the causation of endometrial cancer.St George's Hospital medical schoolNorfolkRecruiting View details
OPAL Older people and n-3 long-chain polyunsaturated fatty acids. OPALLondon Sch Hygiene Tropical Med / MRC-GPRF Closed View details
Outreach A randomised trial comparing delivery of cancer systemic therapy in three different settings: patient's home, general practice surgery and hospital day unit  Set-up View details
P3MC A double blind parallel group randomised placebo controlled trial of Propranolol and Pizotifen in preventing migraine in childrenUniversity of NottinghamEssexSet-up View details
Parent's experience of urgent care services To understand and improve the experience of parents and carers who need advice when a child has a fever (high temperature)  CambsRecruiting View details
Partners Developing integrated care in primary care for people with serious mental illness Cambs
Beds
Set-up View details
Past BP RCT of different blood pressure targets for people with a history of strokeUniversity of BirminghamCambsSet-up View details
PATHWAY 1 Comparison of Combination and Monotherapy for Initial Treatment of HypertensionCambridge University Set-up View details
PATHWAY 2 Optimal treatment of drug resistant hypertension Cambridge University Recruiting View details
PATHWAY 3 Comparison of single and combination diuretics in therapy in low-renin hypertensionCambridge University Set-up View details
Patients' Expectations The measurement of patients? expectations for health careUCLEssex
Norfolk
Recruiting View details
PCRN01 ARRIVE Aspirin to Reduce Risk of Initial Vascular Events -A Randomized, Double-Blind, Placebo Controlled, Multicenter, Parallel Group Study to Assess the Efficacy (Reduction of Cardiovascular Disease Events) and Safety of 100 mg Enteric-Coated AcetylsalicylicBAYER Healthcare AGCambs
Essex
Herts
Norfolk
Recruiting View details
PCRN02 EPI-STREP (AOM) Epidemiological, multi-country, multi-centre, observational, cohort study to evaluate the incidence, clinical and economic burden of acute otitis media (AOM) in subjects aged 0-5 years of age in several European countriesINDUSTRYCambs
Essex
Recruiting View details
PCRN03 PREMIUM A comparison of blood pressure lowering efficacy and safety. A randomised, double-blind, 9 month study of the efficacy and safety of four uptitrated doses of oral fixed combinations of medications in mild to moderate hypertension a comparison of blood pressure lowering efficacy and safetyINDUSTRYSuffolk
Herts
Recruiting View details
PCRN06 Signify' study    View details
PET Genetic Risk And Behaviour change Using genotype to tailor prescribing of NRT: a randomised controlled trial assessing impact upon medication adherence  Follow-up View details
Pharmacogenetics of Warfarin? Variability in response to warfarin: a prospective analysis of pharmacogenetic and environmental factorsUniversity of Birmingham  Follow-up View details
Phase III RCT BIS Phase III randomised controlled trial of a breathlessness intervention service for intractable breathlessness Cambridge University CambsRecruiting View details
POPP_local Local Evaluation of Norfolk Partnerships for Older People Project: At Home Not AloneCordis Bright Pending View details
Proactive Follow-up Proactive: Follow-up studyCambridge University/MRC Epidemiology Unit Recruiting View details
ProCEED Evaluation of a system of structured, pro-active care for chronic depression in primary care  Follow-up View details
ProtecT Evaluating population-based screening for localised prostate cancer in the United Kingdom: an extension to the ProtecT treatment trial; application for case-note reviewBristol UniversitySuffolkSet-up View details
ProtecT The ProtecT Trial - Evaluating the effectiveness of treatment for clinically localised Prostate cancer.Royal Hallamshire Hospital, Sheffield Follow-up View details
Psych-BTS Rates of Psychiatric Illness in Long-term Survivors of Early Childhood Brain TumoursCambridge UniversityBeds
Cambs
Essex
Herts
Norfolk
Suffolk
Recruiting View details
Q-CHAT Development and Assessment of the quantitative checklist for Autism in ToddlersCambridge UniversityCambs
Herts
Beds
Recruiting View details
QOF Depression Study Treatment of depression according to severity  Closed View details
RAMS study Rheumatoid Arthritis Methotrexate Starters (RAMS) cohort study: predicting response to Methotrexate in rheumatoid arthritis  Cambs  View details
RAPID TIA Papid Primary Care Initiation of Drug treatment for TIA - a quantitive prelude to a pilot randomised controlled trial Cambridge universityCambsRecruiting View details
RAPSID Can peer support, delivered as a group or individual intervention, enable people with diabetes and improve their health? (A RAndomised controlled trial of Peer Support In Type 2 Diabetes)Cambridge UniversityCambsRecruiting View details
RISCK Impact of the amount and composition of dietary fat and carbohydrate on metabolic syndrome and cardiovascular disease risk. (The RISCK study)Cambridge University Closed View details
SAMS 2 Use of a blister pack recording device to measure tablet taking behaviour in patients with type 2 diabetes: a proof-of-concept study in UK general practiceUniversity of Oxford Follow-up View details
SATURN Saturn- A follow up programme for patients using Symbicort Turbohaler maintainance and reliever therapy in normal clinical practice    View details
SCJS Study of Suicide in the Criminal Justice System: Nested Case-control   Set-up View details
SCOOP (SCreening Of Older women for the Prevention of fracture) - a pragmatic RCT of the effectiveness and cost effectiveness of screening for osteoporosis in older womenUEANorfolk
Suffolk
Recruiting View details
SEARCH A population based study of genetic predispositions and gene-environment interactions in breast cancer in East Anglia - A population based study of genetic predisposition and gene-environment interactions in colorectal cancer - A population based study of genetic predisposition and gene-environment interactions in endometrial cancer - A population based study of genetic predisposition and gene-environment interactions in ovarian cancer. Cambridge UniversityNorfolk
Cambs
Herts
Essex
Suffolk
Beds
Recruiting View details
SNIFS A primary care RCT of Steam inhalation and Nasal Irrigation For recurrent Sinusitis University of Southampton  Set-up View details
SPeEDS Assisted eating and drinking in the care of people with profound and multiple disabilities: the social significance of clinical interventions for managing dysphagiaCambridge UniversityCambs
Herts
Essex
Set-up View details
Stepped Care for Mental Health Developing evidence based and acceptable stepped care systems in mental health care: an operational research project   Recruiting View details
Stop and Think/AIM (Automated Intention Monitoring) A randomised controlled trial of the impact of electronically delivered 'content free' cueing on psychological functioning following brain injury  Recruiting View details
SWET A multi-centre randomised controlled trial of ion-exchange water softeners for the treatment of eczema in childrenNottingham University CambsRecruiting View details
Swine Flu during Pregnancy Study Influenza A/H1N1v in pregnancy: An investigation of the characteristics and management of affected women and the relationship to pregnancy outcomes for mother and infantNewcastle Hospitals NHS Foundation TrustBeds
Cambs
Essex
Herts
Suffolk
Norfolk
Recruiting View details
TAKL an investigation of the safety and efficacy of oral AKL1 in patients diagnosed with obstructive lung disease   Pending View details
TASTE Treatment Alternative for Sore Throat in Everyday PracticeUniversity of SouthamptonNorfolk
Suffolk
Cambs
Essex
Herts
Recruiting View details
The EQUIP Study Enhancing the Quality of Information-sharing in Primary care for children with respiratory tract infections.Cardiff University Closed View details
The FAST Study Development and validation of a short family history screening tool for chronic disease prevention in primary care.Cambridge UniversityHerts
Essex
Set-up View details
The Million Women Study: Disease Susceptibility in Women The Million Women Study: Detailed Investigation of Susceptibility to DiseaseSouth West Oxfordshire PCT/ Oxford UniversityNorfolk
Cambs
Herts
Essex
Suffolk
Recruiting View details
The MiQuit study The Mi-quit study: feasibility trial of a computer?tailored smoking cessation intervention providing individualised written and mobile phone text message support to pregnant smokersUniversity of Cambridge Recruiting View details
The OPEN Study The open study- Older people and enhanced neurocognitive function study London School of Hygiene and Tropical MedicineEssexRecruiting View details
Think Aloud The use of graphics to support health risk communication:an exploratory study using verbal protocolsCambridge University Recruiting View details
TIPAC Treating Interstital Pneumonia with the Addition of Co-Trimoazole (TIPAC) Study     View details
TOPIC    Set-up View details
TRACE RA Trial of Atorvastatin for the primary prevention of Cardiovascular Events in Rheumatoid Arthritis University of ManchesterDudley Group of Hospitals NHS Trust   View details
TXT2STOP Stop Smoking with Mobile Phones: A randomised controlled trial of mobile phone text messaging to support smoking cessation in young people in the UK London School of Hygiene and Tropical MedicineNorfolk
Herts
Follow-up View details
UKFOCCS The UK Familial Ovarian Cancer Screening Study (UKFOCSS)UCLNorfolk
Cambs
Recruiting View details
VenUS II VenUS II (Venous Ulcer Studies) - Larval Therapy: A randomised controlled trial of larval therapy in the management of Leg UlcersUniversity of York Closed View details
VenUS III VenUS III (Venous Ulcer Studies) - Ultrasound for venous leg ulcers.University of York Follow-up View details
vestibular The benefit of early intervention in the community for patients who require vestibular rehabilitation to treat their balance problems  Pending View details
VIDEO A randomised, double-blind, placebo controlled trial of Vitamin D supplementation in the management of symptomatic knee osteoarthritis (VIDEO)University of East Anglia Follow-up View details
Voices Voices on Identity, Childhood, Ethics and Self: Children Join the Debate   Pending View details
WHOLEheart Randomised controlled trial to test the impact of increased consumption of wholegrain foods on cardiovascular disease risk (the WHOLEheart study) -check pfolioNewcastle University Closed View details